TY - JOUR AU - Dorji, Kuenzang AU - Sharma, Krishna Prasad AU - Jamtsho, Rinzin AU - Samal, Puja Devi AU - Wangchuk, Dorji AU - Rai, Pratap PY - 2016/11/13 Y2 - 2024/03/28 TI - Incidence and pattern of leukemia in Bhutanese population: a retrospective analysis of eight years (January 2008 to December 2015) JF - Bhutan Health Journal JA - Bhutan Health Journal VL - 2 IS - 2 SE - Original Article DO - 10.47811/bhj.27 UR - https://bhj.com.bt/index.php/bhj/article/view/28 SP - 6-9 AB - <p>In<strong>troduction:</strong> The burden of haematological malignancies in developing countries is on the rise. This burden may be further aggravated in Bhutan due to the aging population and rapid modernization of the nation. Despite this, there is a paucity of information about the incidence and pattern of leukemia in the Bhutanese population. In this retrospective study, we aim to investigate the incidence and pattern of leukemia in Bhutan using a database of leukemia diagnosed at Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan from January 2008 to December 2015.</p><p><strong>Methods:</strong> The diagnoses and classification of leukemias were based on the morphology of blood cells on peripheral blood and bone marrow smears. The data was analyzed with descriptive statistics. The age-standardized incidence rate per 100,000 populations and its 95% confidence interval was calculated to assess the statistical significance.</p><p><strong> Results:</strong> In total 118 patients were diagnosed with leukemia over the period of eight years. Leukemia was found to be more frequent in male (51.69%) compared to female (48.30%) with a male to female ratio of 1.1:1. Acute leukemia accounted for 66.95% of all leukemia case diagnosed, whereas chronic leukemia accounted for only 33.05% of the cases. The average, annual, age-standardized incidence rate of leukemia per 100,<br>000 population was 2.30 (95% CI: 1.87-2.73).</p><p><strong> Conclusions:</strong> The incidence and pattern of leukemia in the Bhutanese population is similar to other published literature. Leukemia is not uncommon in the Bhutanese population, thus additional studies on risk factors for leukemia in the Bhutanese population is necessary.</p> ER -