Hypokalemic Periodic Parlaysis Associated with Adrenal Adenoma in a Patient with Conn’s Syndrome: A Case Report

Hypokalemic Periodic Parlaysis Associated with Adrenal Adenoma in a Patient with Conn’s Syndrome: A Case Report

Authors

  • Samuel Noklang Zion Hospital and Research Centre, Nagaland, India
  • Pankaj Kumar Kannauje Pankaj Department Of General medicine, AIIMS Raipur https://orcid.org/0000-0002-2105-5831
  • Shruthi J Rajarajeshwari Medical College and Hospital, Bangalore, India https://orcid.org/0000-0003-2081-3634
  • Imjungba Noklang Zion hospital and Research Centre, Nagaland, India
  • Tepukiel Zaphu Zion hospital and Research Centre, Nagaland, India
  • Nishini Nekha Zion hospital and Research Centre, Nagaland, India
  • Lijanthung S Kithan Zion hospital and Research Centre, Nagaland, India
  • Manong Chowanglim Zion Hospital and Research Centre, Nagaland, India

DOI:

https://doi.org/10.47811/bhj.180

Keywords:

Adrenal Adenoma; Aldosteronism; Hypokalemia; Hypertension; Periodic Paralysis

Abstract

Introduction: Hypokalemic paralysis secondary to Conn’s syndrome is rare. The most common presentation of this condition is hypertension, which may be asymptomatic or range from mild to severe to refractory. Case Report: A 34-year-old hypertensive female presented with acute onset of lower limb weakness. She reported two similar episodes in the past. She had profound hypokalemia and further evaluation revealed high aldosterone and low renin levels, suggesting an adrenal adenoma. She was managed with antihypertensives and spironolactone. After CT confirmation of a right adrenal adenoma, she underwent surgery. She showed significant improvement in both her symptoms and laboratory parameters after surgery, and is doing well on her follow-up. Conclusion: This case illustrates that a high index of suspicion leads to early recognition and timely management of an unusual and potentially severe clinical manifestation of primary hyperaldosteronism in the form of hypokalemic periodic paralysis, especially in the setting of unexplained hypertension.

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Author Biographies

Samuel Noklang, Zion Hospital and Research Centre, Nagaland, India

Department of General Medicine, consultant

Shruthi J, Rajarajeshwari Medical College and Hospital, Bangalore, India

Consultant, Department of Endocrinology

Imjungba Noklang, Zion hospital and Research Centre, Nagaland, India

Department of General Surgery

Tepukiel Zaphu, Zion hospital and Research Centre, Nagaland, India

Department of Urology, consultant

Nishini Nekha, Zion hospital and Research Centre, Nagaland, India

Department of Radiology, consultant

Lijanthung S Kithan, Zion hospital and Research Centre, Nagaland, India

Department of Pathology and Lab medicine, consultant

Manong Chowanglim, Zion Hospital and Research Centre, Nagaland, India

Department of Nephrology, consultant

Published

2025-02-16

How to Cite

1.
Noklang S, Pankaj PKK, Shruthi J, Noklang I, Zaphu T, Nekha N, et al. Hypokalemic Periodic Parlaysis Associated with Adrenal Adenoma in a Patient with Conn’s Syndrome: A Case Report. Bhutan Health Journal [Internet]. 2025 Feb. 16 [cited 2025 May 31];11(1):9. Available from: https://bhj.com.bt/index.php/bhj/article/view/448

Issue

Section

Case Report
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